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In four recent placebo-controlled clinical trials, dysesthesia, an unpleasant sensation that's perceived on or under the skin, was reported as a side effect of the GLP-1 agonist semaglutide in 5-23% of recipients.

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GLP-1 medications like Ozempic, Wegovy and Mounjaro are changing diabetes and weight management, but they aren't recommended during pregnancy or while nursing. The current recommendation is to stop before conception and discuss

Exploration of the potential association between GLP-1 receptor agonists and suicidal or self-injurious behaviors: a pharmacovigilance study based on the FDA Adverse Event Reporting System database | BMC Medicine | Springer Nature

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